Reduced parietal activation in cervical dystonia after parietal TMS interleaved with fMRI

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Reduced parietal activation in cervical dystonia after parietal TMS interleaved with fMRI

OBJECTIVE Clinically normal hand movement with altered cerebral activation patterns in cervical dystonia (CD) may imply cerebral adaptation. Since impaired sensorimotor integration appears to play a role in dystonia, left superior parietal cortex modulation with repetitive transcranial magnetic stimulation (TMS) was employed to further challenge adaptation mechanisms reflected by changes in cer...

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80 Abstract Clinically normal hand movement associated with altered cerebral activation patterns in CD may imply cerebral adaptation. Since impaired sensorimotor integration appears to play a role in dystonia, left superior parietal cortex modulation with TMS was employed to further challenge adaptation mechanisms reflected by a change in cerebral activation. Seven CD patients and ten HC were s...

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Interhemispheric effect of parietal TMS on somatosensory response confirmed directly with concurrent TMS-fMRI.

Transcranial magnetic stimulation (TMS) has been used to document some apparent interhemispheric influences behaviorally, with TMS over the right parietal cortex reported to enhance processing of touch for the ipsilateral right hand (Seyal et al., 1995). However, the neural bases of such apparent interhemispheric influences from TMS remain unknown. Here, we studied this directly by combining TM...

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ژورنال

عنوان ژورنال: Clinical Neurology and Neurosurgery

سال: 2012

ISSN: 0303-8467

DOI: 10.1016/j.clineuro.2012.02.006